Hiroshi Nakajima Selected Research

oxatomide

2/2005	Identification of human P450 isoforms involved in the metabolism of the antiallergic drug, oxatomide, and its kinetic parameters and inhibition constants.
5/2004	Identification of human p450 isoforms involved in the metabolism of the antiallergic drug, oxatomide, and its inhibitory effect on enzyme activity.

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Hiroshi Nakajima Research Topics

Disease

45	Inflammation (Inflammations) 10/2022 - 05/2002
19	Asthma (Bronchial Asthma) 01/2019 - 01/2007
16	Rheumatoid Arthritis 01/2022 - 04/2002
7	Surgical Wound Infection 01/2022 - 04/2016
7	Heart Failure 10/2019 - 02/2010
4	Dermatomyositis (Dermatopolymyositis) 11/2022 - 01/2015
4	Polymyositis 11/2022 - 03/2014
4	Systemic Lupus Erythematosus (Libman-Sacks Disease) 07/2022 - 01/2013
4	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 04/2022 - 12/2017
4	Hypersensitivity (Allergy) 12/2021 - 05/2004
4	Neoplasms (Cancer) 02/2018 - 01/2003
4	Infections 07/2017 - 06/2002
4	Autoimmune Diseases (Autoimmune Disease) 02/2015 - 06/2008
4	Squamous Cell Carcinoma of Head and Neck 09/2014 - 07/2012
4	Hyperplasia 11/2011 - 09/2006
3	Arthritis (Polyarthritis) 01/2022 - 01/2013
3	Myocardial Infarction 10/2021 - 03/2012
3	Atopic Dermatitis (Atopic Eczema) 01/2021 - 01/2002
3	Synovitis 01/2021 - 04/2013
3	Glomerulonephritis 01/2021 - 10/2019
3	Vasculitis (Vasculitides) 03/2020 - 03/2016
3	Diabetes Mellitus 01/2013 - 05/2005
2	Necrosis 08/2022 - 08/2008
2	Myositis (Idiopathic Inflammatory Myopathies) 01/2022 - 03/2014
2	COVID-19 01/2022 - 12/2021
2	Interstitial Lung Diseases (Interstitial Lung Disease) 12/2021 - 10/2021
2	Dermatitis 01/2021 - 01/2002
2	Hemorrhage 01/2021 - 10/2003
2	Thrombosis (Thrombus) 02/2018 - 06/2003
2	Fibrosis (Cirrhosis) 01/2018 - 11/2013
2	Pneumonia (Pneumonitis) 11/2017 - 07/2015
2	Contact Dermatitis (Eczema, Contact) 07/2017 - 05/2015
2	Lymphopenia (Lymphocytopenia) 12/2016 - 04/2016
2	Coronary Artery Disease (Coronary Atherosclerosis) 07/2014 - 01/2014
2	Clubfoot (Talipes Equinovarus) 07/2013 - 01/2013
2	Atrial Fibrillation 01/2013 - 01/2004
2	Immunoglobulin G4-Related Disease 01/2012 - 01/2010
2	Hepatitis 01/2010 - 08/2008
2	Autoimmune Hepatitis 08/2008 - 09/2006
2	Eosinophilia 06/2008 - 01/2006

Drug/Important Bio-Agent (IBA)

25	CytokinesIBA 01/2022 - 01/2002
12	AntigensIBA 01/2019 - 09/2006
11	Interleukin-13IBA 01/2019 - 01/2002
10	Interleukin-5 (Interleukin 5)IBA 01/2019 - 01/2003
9	Interleukin-4 (Interleukin 4)IBA 01/2019 - 01/2002
8	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2014
7	GlucocorticoidsIBA 12/2021 - 01/2013
7	Interleukin-17 (Interleukin 17)IBA 01/2017 - 01/2006
6	Pharmaceutical PreparationsIBA 08/2022 - 02/2010
6	DNA (Deoxyribonucleic Acid)IBA 07/2022 - 08/2002
6	Methotrexate (Mexate)FDA LinkGeneric 01/2022 - 04/2002
6	Interleukin-22 (IL-22)IBA 01/2019 - 11/2011
6	Immunoglobulin E (IgE)IBA 01/2017 - 01/2002
5	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 03/2020 - 10/2003
5	Biological ProductsIBA 06/2015 - 12/2013
4	Rituximab (Mabthera)FDA Link 10/2021 - 12/2017
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 10/2021 - 10/2003
4	AutoantibodiesIBA 01/2021 - 09/2006
4	InterleukinsIBA 01/2018 - 01/2006
4	Interleukin-33IBA 01/2018 - 01/2007
4	AllergensIBA 01/2018 - 11/2008
4	Proteins (Proteins, Gene)FDA Link 03/2014 - 09/2006
3	tocilizumab (atlizumab)FDA Link 08/2022 - 06/2014
3	interleukin-21 (interleukin 21)IBA 10/2021 - 08/2014
3	ChemokinesIBA 01/2021 - 09/2008
3	Thymic Stromal LymphopoietinIBA 01/2021 - 01/2007
3	Interleukin-6 (Interleukin 6)IBA 01/2021 - 05/2014
3	GadoliniumIBA 08/2013 - 01/2012
3	Interleukin-23 (Interleukin 23)IBA 02/2010 - 11/2008
2	Fatty Acids (Saturated Fatty Acids)IBA 10/2022 - 05/2002
2	tofacitinibIBA 08/2022 - 12/2021
2	Tumor Necrosis Factor InhibitorsIBA 08/2022 - 12/2013
2	Imiquimod (Aldara)FDA LinkGeneric 01/2022 - 01/2021
2	Glycoproteins (Glycoprotein)IBA 01/2022 - 01/2019
2	Methylprednisolone FDA LinkGeneric 01/2022 - 10/2021
2	Interleukin-9 (Interleukin 9)IBA 01/2021 - 04/2017
2	C-Reactive ProteinIBA 03/2020 - 04/2016
2	Galactoside 2-alpha-L-fucosyltransferase (Fucosyltransferase 2)IBA 01/2020 - 01/2019
2	Immunosuppressive Agents (Immunosuppressants)IBA 01/2018 - 01/2013
2	Matrix Metalloproteinase 12IBA 07/2017 - 05/2015
2	dectin 1IBA 01/2017 - 01/2017
2	C-Type Lectins (C-Type Lectin)IBA 01/2017 - 08/2014
2	Peroxidase (Myeloperoxidase)IBA 03/2016 - 10/2003
2	SteroidsIBA 11/2015 - 01/2005
2	titanium dioxide (Titania)FDA Link 07/2015 - 09/2014
2	thiazolyl blueIBA 09/2014 - 07/2014
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2014 - 11/2008
2	ResistinIBA 02/2014 - 01/2013
2	Penicillamine (Cuprimine)FDA Link 03/2013 - 10/2003
2	Triglycerides (Triacylglycerol)IBA 01/2012 - 05/2002
2	IonsIBA 07/2010 - 06/2003
2	STAT6 Transcription FactorIBA 03/2007 - 09/2006

Therapy/Procedure

15	Therapeutics 07/2022 - 08/2002
3	Remission Induction 10/2021 - 12/2017
2	Decompression 01/2022 - 01/2018
2	Length of Stay 12/2020 - 07/2015
2	Spinal Fusion (Spondylosyndesis) 01/2018 - 07/2016
2	Tenotomy 07/2013 - 01/2013
2	Cardiac Resynchronization Therapy 01/2013 - 02/2010
2	Defibrillators (Defibrillator) 01/2013 - 02/2010